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It is important to analyze the growth of phytoplankton, which is the primary producer in the ocean, as well as the characteristics of the limiting nutrients that affect it. This can help to understand the process of energy transfer through the food web and is useful for assessing the marine environment. The East/Japan Sea is a semi-enclosed marginal sea surrounded by Asian continent and Japanese Islands. Although it is smaller than other ocean, it is called “Miniature Ocean” because of its unique physical phenomena and biological characteristics (Ichiye et al., 1984). This region is experiencing a rapid increase of sea surface temperature due to climate change. Therefore, studies on the long-term changes of phytoplankton and nutrients in the East/Japan Sea can help predict variations in ocean resources, and furthermore, the effects of climate change on human activities. In this study, we analyzed the variability and trend of nitrate and phosphate EOF(Empirical Orthogonal Functions) analysis on Serial Oceanographic Observation data provided by KODC (Korea Oceanographic Data Center). Chlorophyll-a concentration from satellite was also used as an indicator of phytoplankton biomass. In addition, we have evaluated the performance of CMIP6 (Coupled Model Intercomparison Project phase 6) models using observational data, and identified the variability of the future marine ecosystem environment due to climate change using CMIP6 data that simulate the biogeochemical properties in the East/Japan Sea well. <Reference>ICHIYE, Takashi. Some problems of circulation and hydrography of the Japan Sea and the Tsushima Current. In: Elsevier oceanography series. Elsevier, 1984. p. 15-54.